Activation of α7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E(2 )in rat microglial cultures

BACKGROUND: Nicotinic acetylcholine (Ach) receptors are ligand-gated pentameric ion channels whose main function is to transmit signals for the neurotransmitter Ach in peripheral and central nervous system. However, the α7 nicotinic receptor has been recently found in several non-neuronal cells and...

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Detalles Bibliográficos
Autores principales: De Simone, Roberta, Ajmone-Cat, Maria Antonietta, Carnevale, Daniela, Minghetti, Luisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548670/
https://www.ncbi.nlm.nih.gov/pubmed/15670336
http://dx.doi.org/10.1186/1742-2094-2-4

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