Penetration and distribution of gadolinium-based contrast agents into the cerebrospinal fluid in healthy rats: a potential pathway of entry into the brain tissue

OBJECTIVE: Signal hyperintensity on unenhanced MRI in certain brain regions has been reported after multiple administrations of some, but not all, gadolinium-based contrast agents (GBCAs). One potential initial pathway of GBCA entry into the brain, infiltration from blood into the cerebrospinal flui...

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Detalles Bibliográficos
Autores principales: Jost, Gregor, Frenzel, Thomas, Lohrke, Jessica, Lenhard, Diana Constanze, Naganawa, Shinji, Pietsch, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Contrast Media
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486780/
https://www.ncbi.nlm.nih.gov/pubmed/27832312
http://dx.doi.org/10.1007/s00330-016-4654-2

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