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A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis
A conditional-lethal recombinant virus was constructed in which the expression of the vaccinia virus I7L gene is under the control of the tetracycline operator/repressor system. In the absence of I7L expression, processing of the major VV core proteins is inhibited and electron microscopy reveals de...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548685/ https://www.ncbi.nlm.nih.gov/pubmed/15701171 http://dx.doi.org/10.1186/1743-422X-2-4 |