The role of beta-arrestin2 in shaping fMRI BOLD responses to dopaminergic stimulation

RATIONALE: The dopamine D(2) receptor (D(2)R) couples to inhibitory G(i/o) proteins and is targeted by antipsychotic and antiparkinsonian drugs. Beta-arrestin2 binds to the intracellular regions of the agonist-occupied D(2)R to terminate G protein activation and promote internalization, but also to...

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Detalles Bibliográficos
Autores principales: Sahlholm, Kristoffer, Ielacqua, Giovanna D., Xu, Jinbin, Jones, Lynne A., Schlegel, Felix, Mach, Robert H., Rudin, Markus, Schroeter, Aileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486931/
https://www.ncbi.nlm.nih.gov/pubmed/28382543
http://dx.doi.org/10.1007/s00213-017-4609-6

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