Fatty acid synthase reprograms the epigenome in uterine leiomyosarcomas

SK-UT-1 uterine leiomyosarcomas (Ut-LMS) cells were transduced with a fatty acid synthase (FASN)-containing retroviral vector to recapitulate the “lipogenic phenotype of cancer.” Consistent with this model, forced expression of FASN enhanced SK-UT-1 proliferation, migration, and cellular motion. Fur...

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Detalles Bibliográficos
Autores principales: Guan, Min, Wu, Xiwei, Chu, Peiguo, Chow, Warren A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487038/
https://www.ncbi.nlm.nih.gov/pubmed/28654693
http://dx.doi.org/10.1371/journal.pone.0179692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487038/
https://www.ncbi.nlm.nih.gov/pubmed/28654693
http://dx.doi.org/10.1371/journal.pone.0179692

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