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Fatty acid synthase reprograms the epigenome in uterine leiomyosarcomas

SK-UT-1 uterine leiomyosarcomas (Ut-LMS) cells were transduced with a fatty acid synthase (FASN)-containing retroviral vector to recapitulate the “lipogenic phenotype of cancer.” Consistent with this model, forced expression of FASN enhanced SK-UT-1 proliferation, migration, and cellular motion. Fur...

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Detalles Bibliográficos
Autores principales:	Guan, Min, Wu, Xiwei, Chu, Peiguo, Chow, Warren A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487038/ https://www.ncbi.nlm.nih.gov/pubmed/28654693 http://dx.doi.org/10.1371/journal.pone.0179692

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