Effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology

BACKGROUND: After thoracic surgery, adhesions between the pleura can cause substantial complications. This study investigated the effectiveness of a novel membrane utilizing surface water induction technology to prevent adhesions. METHODS: Eight beagles were divided into an experimental group (five...

Descripción completa

Detalles Bibliográficos
Autores principales: Uemura, Akiko, Nakata, Mary, Goya, Seijirow, Fukayama, Toshiharu, Tanaka, Ryou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487045/
https://www.ncbi.nlm.nih.gov/pubmed/28654705
http://dx.doi.org/10.1371/journal.pone.0179815
_version_ 1783246379266605056
author Uemura, Akiko
Nakata, Mary
Goya, Seijirow
Fukayama, Toshiharu
Tanaka, Ryou
author_facet Uemura, Akiko
Nakata, Mary
Goya, Seijirow
Fukayama, Toshiharu
Tanaka, Ryou
author_sort Uemura, Akiko
collection PubMed
description BACKGROUND: After thoracic surgery, adhesions between the pleura can cause substantial complications. This study investigated the effectiveness of a novel membrane utilizing surface water induction technology to prevent adhesions. METHODS: Eight beagles were divided into an experimental group (five males) and a control group (three females). The experimental group underwent thoracotomy on both the left and right sides of the chest. Both sides received the membrane, and the membrane on one side was glued to the pleura using tissue adhesive. The control group underwent thoracotomy only on the left side. Two weeks postoperatively, all dogs were sacrificed and adhesions were evaluated macroscopically and microscopically. RESULTS: Severe adhesion was seen between the parietal and visceral pleura in all control dogs, whereas the experimental group showed minor adhesion in only one dog on one side. CONCLUSIONS: Our novel anti-adhesive membrane appeared highly effective in preventing postthoracotomy pleural adhesions.
format Online
Article
Text
id pubmed-5487045
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-54870452017-07-11 Effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology Uemura, Akiko Nakata, Mary Goya, Seijirow Fukayama, Toshiharu Tanaka, Ryou PLoS One Research Article BACKGROUND: After thoracic surgery, adhesions between the pleura can cause substantial complications. This study investigated the effectiveness of a novel membrane utilizing surface water induction technology to prevent adhesions. METHODS: Eight beagles were divided into an experimental group (five males) and a control group (three females). The experimental group underwent thoracotomy on both the left and right sides of the chest. Both sides received the membrane, and the membrane on one side was glued to the pleura using tissue adhesive. The control group underwent thoracotomy only on the left side. Two weeks postoperatively, all dogs were sacrificed and adhesions were evaluated macroscopically and microscopically. RESULTS: Severe adhesion was seen between the parietal and visceral pleura in all control dogs, whereas the experimental group showed minor adhesion in only one dog on one side. CONCLUSIONS: Our novel anti-adhesive membrane appeared highly effective in preventing postthoracotomy pleural adhesions. Public Library of Science 2017-06-27 /pmc/articles/PMC5487045/ /pubmed/28654705 http://dx.doi.org/10.1371/journal.pone.0179815 Text en © 2017 Uemura et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Uemura, Akiko
Nakata, Mary
Goya, Seijirow
Fukayama, Toshiharu
Tanaka, Ryou
Effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology
title Effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology
title_full Effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology
title_fullStr Effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology
title_full_unstemmed Effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology
title_short Effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology
title_sort effective new membrane for preventing postthoracotomy pleural adhesion by surface water induction technology
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487045/
https://www.ncbi.nlm.nih.gov/pubmed/28654705
http://dx.doi.org/10.1371/journal.pone.0179815
work_keys_str_mv AT uemuraakiko effectivenewmembraneforpreventingpostthoracotomypleuraladhesionbysurfacewaterinductiontechnology
AT nakatamary effectivenewmembraneforpreventingpostthoracotomypleuraladhesionbysurfacewaterinductiontechnology
AT goyaseijirow effectivenewmembraneforpreventingpostthoracotomypleuraladhesionbysurfacewaterinductiontechnology
AT fukayamatoshiharu effectivenewmembraneforpreventingpostthoracotomypleuraladhesionbysurfacewaterinductiontechnology
AT tanakaryou effectivenewmembraneforpreventingpostthoracotomypleuraladhesionbysurfacewaterinductiontechnology

Ejemplares similares