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Wolf–Hirschhorn Syndrome Candidate 1 (whsc1) Functions as a Tumor Suppressor by Governing Cell Differentiation

Wolf–Hirschhorn syndrome candidate 1 (WHSC1) is a histone 3 lysine 36 (H3K36) specific methyltransferase that is frequently deleted in Wolf–Hirschhorn syndrome (WHS). Whsc1 is also found mutated in a subgroup of B-cell derived malignant diseases by genomic translocation or point mutation, both of wh...

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Detalles Bibliográficos
Autores principales: Yu, Chuan, Yao, Xiaomin, Zhao, Linjie, Wang, Ping, Zhang, Qian, Zhao, Chengjian, Yao, Shaohua, Wei, Yuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487304/
https://www.ncbi.nlm.nih.gov/pubmed/28654864
http://dx.doi.org/10.1016/j.neo.2017.05.001