Cargando…

Oxidative stress induced by UVA photoactivation of the tryptophan UVB photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) inhibits nucleotide excision repair in human cells

Potentially mutagenic DNA lesions induced by UVB (wavelengths 280–320 nm) are important risk factors for solar ultraviolet (UV) radiation-induced skin cancer. The carcinogenicity of the more abundant UVA (320–400 nm) is less well understood but is generally regarded to reflect its interaction with c...

Descripción completa

Detalles Bibliográficos
Autores principales: Brem, Reto, Macpherson, Peter, Guven, Melisa, Karran, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487344/
https://www.ncbi.nlm.nih.gov/pubmed/28655934
http://dx.doi.org/10.1038/s41598-017-04614-8