Synergistic effect of human Bone Morphogenic Protein-2 and Mesenchymal Stromal Cells on chronic wounds through hypoxia-inducible factor-1 α induction

Chronic skin ulcers and burns require advanced treatments. Mesenchymal Stromal Cells (MSCs) are effective in treating these pathologies. Bone Morphogenic Protein-2 (BMP-2) is known to enhance angiogenesis. We investigated whether recombinant human hBMP-2 potentiates the effect of MSCs on wound heali...

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Detalles Bibliográficos
Autores principales: François, Sabine, Eder, Véronique, Belmokhtar, Karim, Machet, Marie-Christine, Douay, Luc, Gorin, Norbert-Claude, Benderitter, Marc, Chapel, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487365/
https://www.ncbi.nlm.nih.gov/pubmed/28655873
http://dx.doi.org/10.1038/s41598-017-04496-w

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