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Alloantigen-Induced Regulatory T Cells Generated in Presence of Vitamin C Display Enhanced Stability of Foxp3 Expression and Promote Skin Allograft Acceptance
Regulatory T cells (Tregs) are critical for the maintenance of immune homeostasis and self-tolerance and can be therapeutically used for prevention of unwanted immune responses such as allotransplant rejection. Tregs are characterized by expression of the transcription factor Foxp3, and recent work...
Autores principales: | Nikolouli, Eirini, Hardtke-Wolenski, Matthias, Hapke, Martin, Beckstette, Michael, Geffers, Robert, Floess, Stefan, Jaeckel, Elmar, Huehn, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487376/ https://www.ncbi.nlm.nih.gov/pubmed/28702031 http://dx.doi.org/10.3389/fimmu.2017.00748 |
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