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Astrocyte Activation in Locus Coeruleus Is Involved in Neuropathic Pain Exacerbation Mediated by Maternal Separation and Social Isolation Stress
Our previous studies demonstrated that emotional dysfunction associated with early life stress exacerbated nerve injury-induced mechanical allodynia. Sex differences were observed in several anxiety tests, but not in mechanical allodynia. To elucidate the mechanism underlying these findings, we have...
Autores principales: | Nakamoto, Kazuo, Aizawa, Fuka, Kinoshita, Megumi, Koyama, Yutaka, Tokuyama, Shogo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487383/ https://www.ncbi.nlm.nih.gov/pubmed/28701953 http://dx.doi.org/10.3389/fphar.2017.00401 |
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