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Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling

Mania causes symptoms of hyperactivity, impulsivity, elevated mood, reduced anxiety and decreased need for sleep, which suggests that the dysfunction of the striatum, a critical component of the brain motor and reward system, can be causally associated with mania. However, detailed molecular pathoph...

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Detalles Bibliográficos
Autores principales: Lee, Yeunkum, Kim, Sun Gyun, Lee, Bokyoung, Zhang, Yinhua, Kim, Yoonhee, Kim, Shinhyun, Kim, Eunjoon, Kang, Hyojin, Han, Kihoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487420/
https://www.ncbi.nlm.nih.gov/pubmed/28701918
http://dx.doi.org/10.3389/fnmol.2017.00201