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Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling
Mania causes symptoms of hyperactivity, impulsivity, elevated mood, reduced anxiety and decreased need for sleep, which suggests that the dysfunction of the striatum, a critical component of the brain motor and reward system, can be causally associated with mania. However, detailed molecular pathoph...
Autores principales: | Lee, Yeunkum, Kim, Sun Gyun, Lee, Bokyoung, Zhang, Yinhua, Kim, Yoonhee, Kim, Shinhyun, Kim, Eunjoon, Kang, Hyojin, Han, Kihoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487420/ https://www.ncbi.nlm.nih.gov/pubmed/28701918 http://dx.doi.org/10.3389/fnmol.2017.00201 |
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