Cargando…
Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways
AIM: To study the molecular mechanisms involved in the hepatoprotective effects of naringenin (NAR) on carbon tetrachloride (CCl(4))-induced liver fibrosis. METHODS: Thirty-two male Wistar rats (120-150 g) were randomly divided into four groups: (1) a control group (n = 8) that received 0.7% carboxy...
Autores principales: | Hernández-Aquino, Erika, Zarco, Natanael, Casas-Grajales, Sael, Ramos-Tovar, Erika, Flores-Beltrán, Rosa E, Arauz, Jonathan, Shibayama, Mineko, Favari, Liliana, Tsutsumi, Víctor, Segovia, José, Muriel, Pablo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487499/ https://www.ncbi.nlm.nih.gov/pubmed/28706418 http://dx.doi.org/10.3748/wjg.v23.i24.4354 |
Ejemplares similares
-
Stevia Prevents Acute and Chronic Liver Injury Induced by Carbon Tetrachloride by Blocking Oxidative Stress through Nrf2 Upregulation
por: Ramos-Tovar, Erika, et al.
Publicado: (2018) -
Beneficial effects of naringenin in liver diseases: Molecular mechanisms
por: Hernández-Aquino, Erika, et al.
Publicado: (2018) -
Treatment of renal fibrosis by rebalancing TGF-β/Smad signaling with the combination of asiatic acid and naringenin
por: Meng, Xiao-ming, et al.
Publicado: (2015) -
The expression of TGF-β1, Smad3, phospho-Smad3 and Smad7 is correlated with the development and invasion of nonfunctioning pituitary adenomas
por: Zhenye, Li, et al.
Publicado: (2014) -
TGF-β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway
por: He, Dengwei, et al.
Publicado: (2021)