Enhancer-derived RNA: A Primer

Enhancer-derived RNAs (eRNAs) are a group of RNAs transcribed by RNA polymerase II from the domain of transcription enhancers, a major type of cis-regulatory elements in the genome. The correlation between eRNA production and enhancer activity has stimulated studies on the potential role of eRNAs in...

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Detalles Bibliográficos
Autor principal: Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487531/
https://www.ncbi.nlm.nih.gov/pubmed/28533025
http://dx.doi.org/10.1016/j.gpb.2016.12.006
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author Liu, Feng
author_facet Liu, Feng
author_sort Liu, Feng
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description Enhancer-derived RNAs (eRNAs) are a group of RNAs transcribed by RNA polymerase II from the domain of transcription enhancers, a major type of cis-regulatory elements in the genome. The correlation between eRNA production and enhancer activity has stimulated studies on the potential role of eRNAs in transcriptional regulation. Additionally, eRNA has also served as a marker for global identification of enhancers. Here I review the brief history and fascinating properties of eRNAs.
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spelling pubmed-54875312017-07-12 Enhancer-derived RNA: A Primer Liu, Feng Genomics Proteomics Bioinformatics Review Enhancer-derived RNAs (eRNAs) are a group of RNAs transcribed by RNA polymerase II from the domain of transcription enhancers, a major type of cis-regulatory elements in the genome. The correlation between eRNA production and enhancer activity has stimulated studies on the potential role of eRNAs in transcriptional regulation. Additionally, eRNA has also served as a marker for global identification of enhancers. Here I review the brief history and fascinating properties of eRNAs. Elsevier 2017-06 2017-05-19 /pmc/articles/PMC5487531/ /pubmed/28533025 http://dx.doi.org/10.1016/j.gpb.2016.12.006 Text en © 2017 The Author http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Liu, Feng
Enhancer-derived RNA: A Primer
title Enhancer-derived RNA: A Primer
title_full Enhancer-derived RNA: A Primer
title_fullStr Enhancer-derived RNA: A Primer
title_full_unstemmed Enhancer-derived RNA: A Primer
title_short Enhancer-derived RNA: A Primer
title_sort enhancer-derived rna: a primer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487531/
https://www.ncbi.nlm.nih.gov/pubmed/28533025
http://dx.doi.org/10.1016/j.gpb.2016.12.006
work_keys_str_mv AT liufeng enhancerderivedrnaaprimer

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