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Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A Virus
The bottleneck governing infectious disease transmission describes the size of the pathogen population transferred from the donor to the recipient host. Accurate quantification of the bottleneck size is particularly important for rapidly evolving pathogens such as influenza virus, as narrow bottlene...
Autores principales: | Sobel Leonard, Ashley, Weissman, Daniel B., Greenbaum, Benjamin, Ghedin, Elodie, Koelle, Katia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487570/ https://www.ncbi.nlm.nih.gov/pubmed/28468874 http://dx.doi.org/10.1128/JVI.00171-17 |
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