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Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A Virus

The bottleneck governing infectious disease transmission describes the size of the pathogen population transferred from the donor to the recipient host. Accurate quantification of the bottleneck size is particularly important for rapidly evolving pathogens such as influenza virus, as narrow bottlene...

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Detalles Bibliográficos
Autores principales:	Sobel Leonard, Ashley, Weissman, Daniel B., Greenbaum, Benjamin, Ghedin, Elodie, Koelle, Katia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487570/ https://www.ncbi.nlm.nih.gov/pubmed/28468874 http://dx.doi.org/10.1128/JVI.00171-17

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