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A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence
This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two compost heaps with contrasting azole exposures: azole free and azole exposed. After heat shock, to which sexual but not asexual spores are highly resistant, the azole-free compost yielded 98% (49/50) wild...
Autores principales: | Zhang, Jianhua, Snelders, Eveline, Zwaan, Bas J., Schoustra, Sijmen E., Meis, Jacques F., van Dijk, Karin, Hagen, Ferry, van der Beek, Martha T., Kampinga, Greetje A., Zoll, Jan, Melchers, Willem J. G., Verweij, Paul E., Debets, Alfons J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487732/ https://www.ncbi.nlm.nih.gov/pubmed/28655821 http://dx.doi.org/10.1128/mBio.00791-17 |
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