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Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity
Neurospora crassa cpc-1 and Saccharomyces cerevisiae GCN4 are homologs specifying transcription activators that drive the transcriptional response to amino acid limitation. The cpc-1 mRNA contains two upstream open reading frames (uORFs) in its >700-nucleotide (nt) 5′ leader, and its expression i...
Autores principales: | Ivanov, Ivaylo P., Wei, Jiajie, Caster, Stephen Z., Smith, Kristina M., Michel, Audrey M., Zhang, Ying, Firth, Andrew E., Freitag, Michael, Dunlap, Jay C., Bell-Pedersen, Deborah, Atkins, John F., Sachs, Matthew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487733/ https://www.ncbi.nlm.nih.gov/pubmed/28655822 http://dx.doi.org/10.1128/mBio.00844-17 |
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