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Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors

The TP53 signal transduction pathway is an attractive target for cancer treatments. In this study, we conducted a comprehensive molecular evaluation of 907 patients with cancer in Japan to identify genomic alterations in the TP53 pathway. TP53 mutations were frequently detected in many cancers, exce...

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Detalles Bibliográficos
Autores principales:	Ohnami, Shumpei, Ohshima, Keiichi, Nagashima, Takeshi, Urakami, Kenichi, Shimoda, Yuji, Saito, Junko, Naruoka, Akane, Hatakeyama, Keiichi, Mochizuki, Tohru, Serizawa, Masakuni, Ohnami, Sumiko, Kusuhara, Masatoshi, Yamaguchi, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487743/ https://www.ncbi.nlm.nih.gov/pubmed/28258440 http://dx.doi.org/10.1007/s11010-017-2977-1

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