Permitting patients to pay for participation in clinical trials: the advent of the P4 trial

In this article we explore the ethical issues raised by permitting patients to pay for participation (P4) in clinical trials, and discuss whether there are any categorical objections to this practice. We address key considerations concerning payment for participation in trials, including patient aut...

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Autores principales: Shaw, David, de Wert, Guido, Dondorp, Wybo, Townend, David, Bos, Gerard, van Gelder, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Scientific Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487744/
https://www.ncbi.nlm.nih.gov/pubmed/27757784
http://dx.doi.org/10.1007/s11019-016-9741-2
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author Shaw, David
de Wert, Guido
Dondorp, Wybo
Townend, David
Bos, Gerard
van Gelder, Michel
author_facet Shaw, David
de Wert, Guido
Dondorp, Wybo
Townend, David
Bos, Gerard
van Gelder, Michel
author_sort Shaw, David
collection PubMed
description In this article we explore the ethical issues raised by permitting patients to pay for participation (P4) in clinical trials, and discuss whether there are any categorical objections to this practice. We address key considerations concerning payment for participation in trials, including patient autonomy, risk/benefit and justice, taking account of two previous critiques of the ethics of P4. We conclude that such trials could be ethical under certain strict conditions, but only if other potential sources of funding have first been explored or are unavailable.
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spelling pubmed-54877442017-07-03 Permitting patients to pay for participation in clinical trials: the advent of the P4 trial Shaw, David de Wert, Guido Dondorp, Wybo Townend, David Bos, Gerard van Gelder, Michel Med Health Care Philos Scientific Contribution In this article we explore the ethical issues raised by permitting patients to pay for participation (P4) in clinical trials, and discuss whether there are any categorical objections to this practice. We address key considerations concerning payment for participation in trials, including patient autonomy, risk/benefit and justice, taking account of two previous critiques of the ethics of P4. We conclude that such trials could be ethical under certain strict conditions, but only if other potential sources of funding have first been explored or are unavailable. Springer Netherlands 2016-10-18 2017 /pmc/articles/PMC5487744/ /pubmed/27757784 http://dx.doi.org/10.1007/s11019-016-9741-2 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Scientific Contribution
Shaw, David
de Wert, Guido
Dondorp, Wybo
Townend, David
Bos, Gerard
van Gelder, Michel
Permitting patients to pay for participation in clinical trials: the advent of the P4 trial
title Permitting patients to pay for participation in clinical trials: the advent of the P4 trial
title_full Permitting patients to pay for participation in clinical trials: the advent of the P4 trial
title_fullStr Permitting patients to pay for participation in clinical trials: the advent of the P4 trial
title_full_unstemmed Permitting patients to pay for participation in clinical trials: the advent of the P4 trial
title_short Permitting patients to pay for participation in clinical trials: the advent of the P4 trial
title_sort permitting patients to pay for participation in clinical trials: the advent of the p4 trial
topic Scientific Contribution
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487744/
https://www.ncbi.nlm.nih.gov/pubmed/27757784
http://dx.doi.org/10.1007/s11019-016-9741-2
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