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Molecular Profiling of Thymoma and Thymic Carcinoma: Genetic Differences and Potential Novel Therapeutic Targets

Thymoma and thymic carcinoma are thymic epithelial tumors (TETs). We performed a molecular profiling to investigate the pathogenesis of TETs and identify novel targets for therapy. We analyzed 37 thymomas (18 type A, 19 type B3) and 35 thymic carcinomas. The sequencing of 50 genes detected nonsynony...

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Detalles Bibliográficos
Autores principales: Enkner, Franz, Pichlhöfer, Bettina, Zaharie, Alexandru Teodor, Krunic, Milica, Holper, Tina Maria, Janik, Stefan, Moser, Bernhard, Schlangen, Karin, Neudert, Barbara, Walter, Karin, Migschitz, Brigitte, Müllauer, Leonhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487866/
https://www.ncbi.nlm.nih.gov/pubmed/27844328
http://dx.doi.org/10.1007/s12253-016-0144-8