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S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion
DNA replication stress, an important source of genomic instability, arises upon different types of DNA replication perturbations, including those that stall replication fork progression. Inhibitors of the cellular pool of deoxynucleotide triphosphates (dNTPs) slow down DNA synthesis throughout the g...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487892/ https://www.ncbi.nlm.nih.gov/pubmed/28220209 http://dx.doi.org/10.1007/s00018-017-2474-4 |