Potential inhibitory effect of indolizine derivatives on the two enzymes: nicotinamide phosphoribosyltransferase and beta lactamase, a molecular dynamics study

Nicotinamide phosphoribosyl-transferases (NAMPT) are enzymes that play a role in targeting cancer metabolism, while beta lactamases are involved in bacterial resistance to beta-lactam antibiotics. Many protein inhibitors exhibit such property which is often correlated with their cellular potency. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Szefler, Beata, Czeleń, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487893/
https://www.ncbi.nlm.nih.gov/pubmed/28634829
http://dx.doi.org/10.1007/s00894-017-3363-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487893/
https://www.ncbi.nlm.nih.gov/pubmed/28634829
http://dx.doi.org/10.1007/s00894-017-3363-3

Ejemplares similares