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Extracellular renalase protects cells and organs by outside‐in signalling
Renalase was discovered as a protein synthesized by the kidney and secreted in blood where it circulates at a concentration of approximately 3–5 μg/ml. Initial reports suggested that it functioned as an NAD(P)H oxidase and could oxidize catecholamines. Administration of renalase lowers blood pressur...
Autores principales: | Wang, Yang, Safirstein, Robert, Velazquez, Heino, Guo, Xiao‐Jia, Hollander, Lindsay, Chang, John, Chen, Tian‐Min, Mu, Jian‐Jun, Desir, Gary V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487909/ https://www.ncbi.nlm.nih.gov/pubmed/28238213 http://dx.doi.org/10.1111/jcmm.13062 |
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