Exposure to 15% oxygen in vivo up‐regulates cardioprotective SUR2A without affecting ERK1/2 and AKT: a crucial role for AMPK

SUR2A is an ‘atypical’ ABC protein that forms sarcolemmal ATP‐sensitive K(+) (K(ATP)) channels by binding to inward rectifier Kir6.2. Manipulation with SUR2A levels has been suggested to be a promising therapeutic strategy against ischaemic heart diseases and other diseases where increased heart res...

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Detalles Bibliográficos
Autores principales: Mohammed Abdul, Khaja Shameem, Jovanović, Sofija, Jovanović, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487919/
https://www.ncbi.nlm.nih.gov/pubmed/28121062
http://dx.doi.org/10.1111/jcmm.13064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487919/
https://www.ncbi.nlm.nih.gov/pubmed/28121062
http://dx.doi.org/10.1111/jcmm.13064

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