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Exposure to 15% oxygen in vivo up‐regulates cardioprotective SUR2A without affecting ERK1/2 and AKT: a crucial role for AMPK
SUR2A is an ‘atypical’ ABC protein that forms sarcolemmal ATP‐sensitive K(+) (K(ATP)) channels by binding to inward rectifier Kir6.2. Manipulation with SUR2A levels has been suggested to be a promising therapeutic strategy against ischaemic heart diseases and other diseases where increased heart res...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487919/ https://www.ncbi.nlm.nih.gov/pubmed/28121062 http://dx.doi.org/10.1111/jcmm.13064 |