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Sample Preparation Strategies for the Effective Quantitation of Hydrophilic Metabolites in Serum by Multi-Targeted HILIC-MS/MS
The effect of endogenous interferences of serum in multi-targeted metabolite profiling HILIC-MS/MS analysis was investigated by studying different sample preparation procedures. A modified QuEChERS dispersive SPE protocol, a HybridSPE protocol, and a combination of liquid extraction with protein pre...
Autores principales: | Tsakelidou, Elisavet, Virgiliou, Christina, Valianou, Lemonia, Gika, Helen G., Raikos, Nikolaos, Theodoridis, Georgios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487984/ https://www.ncbi.nlm.nih.gov/pubmed/28358315 http://dx.doi.org/10.3390/metabo7020013 |
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