Cargando…

A Novel Anti-Hepatitis C Virus and Antiproliferative Agent Alters Metabolic Networks in HepG2 and Hep3B Cells

A series of novel diflunisal hydrazide-hydrazones has been reported together with their anti-hepatitis C virus and antiproliferative activities in a number of human hepatoma cell lines. However, the mechanisms underlying the efficacy of these agents remain unclear. It was chosen to investigate the l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keogh, Adrian, Şenkardeş, Sevil, Idle, Jeffrey R., Küçükgüzel, Ş. Güniz, Beyoğlu, Diren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487994/ https://www.ncbi.nlm.nih.gov/pubmed/28574427 http://dx.doi.org/10.3390/metabo7020023

Ejemplares similares

Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells
por: Dai, Zhi-Jun, et al.
Publicado: (2013)

Antiproliferative and Apoptotic Effects of Cardamonin against Hepatocellular Carcinoma HepG2 Cells
por: Badroon, Nassrin A., et al.
Publicado: (2020)

The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect
por: Wang, Min, et al.
Publicado: (2016)

DNMT1/PKR double knockdowned HepG2 (HepG2-DP) cells have high hepatic function and differentiation ability
por: Tanaka-yachi, Rieko, et al.
Publicado: (2022)

Effect of yellowing time on bioactive compounds in yellow tea and their antiproliferative capacity in HepG2 cells
por: An, Ran, et al.
Publicado: (2019)

Antiproliferative Effects of Ferulic, Coumaric, and Caffeic Acids in HepG2 Cells by hTERT Downregulation
por: Afshari, Afsoon, et al.
Publicado: (2022)

Preparation and Characterization of an Oyster Peptide–Zinc Complex and Its Antiproliferative Activity on HepG(2) Cells
por: Peng, Bo, et al.
Publicado: (2023)

Metabolomic and Lipidomic Biomarkers for Premalignant Liver Disease Diagnosis and Therapy
por: Beyoğlu, Diren, et al.
Publicado: (2020)

Metabolic Rewiring and the Characterization of Oncometabolites
por: Beyoğlu, Diren, et al.
Publicado: (2021)

Anti-tumor effect of volatile oil from Houttuynia cordata Thunb. on HepG2 cells and HepG2 tumor-bearing mice
por: Yang, Linsong, et al.
Publicado: (2019)

TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK–STAT signaling pathway
por: Zhu, X, et al.
Publicado: (2016)

Antiproliferative Activity of the Chinese Medicinal Compound, Delisheng, Compared With Rg3 and Gemcitabine in HepG2 Cells
por: Wang, S. H., et al.
Publicado: (2013)

Antiproliferative Effect of the Isoquinoline Alkaloid Papaverine in Hepatocarcinoma HepG-2 Cells — Inhibition of Telomerase and Induction of Senescence
por: Noureini, Sakineh Kazemi, et al.
Publicado: (2014)

Artificial cells eavesdropping on HepG2 cells
por: Westensee, Isabella Nymann, et al.
Publicado: (2023)

Robust Regression Analysis of GCMS Data Reveals Differential Rewiring of Metabolic Networks in Hepatitis B and C Patients
por: Simillion, Cedric, et al.
Publicado: (2017)

HepG2-NTCP Subclones Exhibiting High Susceptibility to Hepatitis B Virus Infection
por: Zahoor, Muhammad Atif, et al.
Publicado: (2022)

Identification of Target Genes Involved in the Antiproliferative Effect of Enzyme-Modified Ginseng Extract in HepG2 Hepatocarcinoma Cell
por: Jang, Sung-Il, et al.
Publicado: (2013)

Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols
por: Beyoğlu, Diren, et al.
Publicado: (2023)

Lavender Essential Oil Modulates Hepatic Cholesterol Metabolism in HepG2 Cells
por: Martella, Noemi, et al.
Publicado: (2023)

Characterization of dengue virus entry into HepG2 cells
por: Suksanpaisan, Lukkana, et al.
Publicado: (2009)

Selectivity of biopolymer membranes using HepG2 cells
por: Lü, Dongyuan, et al.
Publicado: (2015)

Curcumin Effect on Copper Transport in HepG2 Cells
por: Berzina, Anita, et al.
Publicado: (2018)

Cholesterol-lowing effect of taurine in HepG2 cell
por: Guo, Junxia, et al.
Publicado: (2017)

Nevirapine induced mitochondrial dysfunction in HepG2 cells
por: Paemanee, Atchara, et al.
Publicado: (2017)

The Expectation and Reality of the HepG2 Core Metabolic Profile
por: Kiseleva, Olga I., et al.
Publicado: (2023)

Effects of cordycepin on HepG2 and EA.hy926 cells: Potential antiproliferative, antimetastatic and anti-angiogenic effects on hepatocellular carcinoma
por: LU, HAISHENG, et al.
Publicado: (2014)

Investigation of the anti-cancer effect of quercetin on HepG2 cells in vivo
por: Zhou, Jin, et al.
Publicado: (2017)

Embelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway
por: TAGHIYEV, ASAF, et al.
Publicado: (2012)

Antiproliferative Effect and Mediation of Apoptosis in Human Hepatoma HepG2 Cells Induced by Djulis Husk and Its Bioactive Compounds
por: Tu, Dom-Gene, et al.
Publicado: (2020)

Hydroxyethyl Starch Curcumin Enhances Antiproliferative Effect of Curcumin Against HepG2 Cells via Apoptosis and Autophagy Induction
por: Jiang, Linhai, et al.
Publicado: (2021)

Farnesiferol C Exerts Antiproliferative Effects on Hepatocellular Carcinoma HepG2 Cells by Instigating ROS-Dependent Apoptotic Pathway
por: Alafnan, Ahmed, et al.
Publicado: (2022)

Alterations in cellular and organellar phospholipid compositions of HepG2 cells during cell growth
por: Tsuji, Tokuji, et al.
Publicado: (2021)

Patulin Alters Insulin Signaling and Metabolic Flexibility in HepG2 and HEK293 Cells
por: Pillay, Yashodani, et al.
Publicado: (2023)

Antioxidant Activity of Oat Proteins Derived Peptides in Stressed Hepatic HepG2 Cells
por: Du, Yichen, et al.
Publicado: (2016)

Effects of Lipid Deposition on Viscoelastic Response in Human Hepatic Cell Line HepG2
por: Li, Rui, et al.
Publicado: (2021)

Inhibitory Effect of Styrylpyrone Extract of Phellinus linteus on Hepatic Steatosis in HepG2 Cells
por: Chiu, Chun-Hung, et al.
Publicado: (2023)

HepGentox: a novel promising HepG2 reportergene-assay for the detection of genotoxic substances in complex mixtures
por: Pinter, Elisabeth, et al.
Publicado: (2021)

Lipid synthesis and secretion in HepG2 cells is not affected by ACTH
por: Skoog, Maria, et al.
Publicado: (2010)

Cadmium Impairs p53 Activity in HepG2 Cells
por: Urani, C., et al.
Publicado: (2014)

RNA-Sequencing Analysis of HepG2 Cells Treated with Atorvastatin
por: Stormo, Camilla, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bfl3fdd82vqh8qclk8eeeb9gcc