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Role of Homologous Fc Fragment in the Potency and Efficacy of Anti-Botulinum Antibody Preparations
The only approved treatment for botulism relies on passive immunity which is mostly based on antibody preparations collected from hyper-immune horses. The IgG Fc fragment is commonly removed from these heterologous preparations to reduce the incidence of hyper-sensitivity reactions. New-generation t...
Autores principales: | Torgeman, Amram, Ozeri, Eyal, Ben David, Alon, Diamant, Eran, Rosen, Osnat, Schwartz, Arieh, Barnea, Ada, Makovitzki, Arik, Mimran, Avishai, Zichel, Ran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488030/ https://www.ncbi.nlm.nih.gov/pubmed/28555060 http://dx.doi.org/10.3390/toxins9060180 |
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