Two Saporin-Containing Immunotoxins Specific for CD20 and CD22 Show Different Behavior in Killing Lymphoma Cells

Immunotoxins (ITs) are hybrid proteins combining the binding specificity of antibodies with the cytocidal properties of toxins. They represent a promising approach to lymphoma therapy. The cytotoxicity of two immunotoxins obtained by chemical conjugation of the plant toxin saporin-S6 with the anti-C...

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Detalles Bibliográficos
Autores principales: Polito, Letizia, Mercatelli, Daniele, Bortolotti, Massimo, Maiello, Stefania, Djemil, Alice, Battelli, Maria Giulia, Bolognesi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488032/
https://www.ncbi.nlm.nih.gov/pubmed/28556822
http://dx.doi.org/10.3390/toxins9060182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488032/
https://www.ncbi.nlm.nih.gov/pubmed/28556822
http://dx.doi.org/10.3390/toxins9060182

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