An Arterial Spin Labeling MRI Perfusion Study of Migraine without Aura Attacks

BACKGROUND: Studies of brain perfusion during migraine without aura attacks have inconsistent results. METHODS: Arterial spin labeling MRI, a non-invasive quantitative perfusion technique, was used to prospectively study a spontaneous untreated migraine without aura attack and a headache-free period...

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Detalles Bibliográficos
Autores principales: Gil-Gouveia, Raquel, Pinto, Joana, Figueiredo, Patricia, Vilela, Pedro Ferro, Martins, Isabel Pavão
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488142/
https://www.ncbi.nlm.nih.gov/pubmed/28701991
http://dx.doi.org/10.3389/fneur.2017.00280
Descripción
Sumario:BACKGROUND: Studies of brain perfusion during migraine without aura attacks have inconsistent results. METHODS: Arterial spin labeling MRI, a non-invasive quantitative perfusion technique, was used to prospectively study a spontaneous untreated migraine without aura attack and a headache-free period. Image analysis used FSL and MATLAB software; Group analysis used permutation methods for perfusion differences between sessions. RESULTS: Thirteen women (age 35.7) were scanned during an attack of an average intensity of 6.8 (on 0–10 Visual Analog Scale) and 16 h duration. No global or regional perfusion differences were identified when comparing migraine and migraine-free sessions. DISCUSSION: Our findings suggest that the painful phase of migraine without aura attacks is not associated with brain perfusion abnormalities.

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