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Overexpression of miR-24 Is Involved in the Formation of Hypocoagulation State after Severe Trauma by Inhibiting the Synthesis of Coagulation Factor X

BACKGROUND: Dysregulation of microRNAs may contribute to the progression of trauma-induced coagulopathy (TIC). We aimed to explore the biological function that miRNA-24-3p (miR-24) might have in coagulation factor deficiency after major trauma and TIC. METHODS: 15 healthy volunteers and 36 severe tr...

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Detalles Bibliográficos
Autores principales: Chen, Lu-Jia, Yang, Lian, Cheng, Xing, Xue, Yin-Kai, Chen, Li-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488151/
https://www.ncbi.nlm.nih.gov/pubmed/28694557
http://dx.doi.org/10.1155/2017/3649693