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Arrhythmic effects of Epac‐mediated ryanodine receptor activation in Langendorff‐perfused murine hearts are associated with reduced conduction velocity

Recent papers have attributed arrhythmic substrate in murine RyR2‐P2328S hearts to reduced action potential (AP) conduction velocities (CV), reflecting acute functional inhibition and/or reduced expression of sodium channels. We explored for acute effects of direct exchange protein directly activate...

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Detalles Bibliográficos
Autores principales: Li, Mengye, Hothi, Sandeep S, Salvage, Samantha C, Jeevaratnam, Kamalan, Grace, Andrew A, Huang, Christopher L‐H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488224/
https://www.ncbi.nlm.nih.gov/pubmed/28316073
http://dx.doi.org/10.1111/1440-1681.12751

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