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The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats’ retinal ganglion cells after ischemia and reperfusion injury
BACKGROUND: The endogenously produced gaseous molecule carbon monoxide is able to promote organ protection after ischemia-reperfusion injuries (IRI). The impact of carbon monoxide releasing molecules (CORM) regarding inflammation in neuronal tissues has not been studied in detail. In this investigat...
Autores principales: | Ulbrich, Felix, Hagmann, Claus, Buerkle, Hartmut, Romao, Carlos C., Schallner, Nils, Goebel, Ulrich, Biermann, Julia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488359/ https://www.ncbi.nlm.nih.gov/pubmed/28655348 http://dx.doi.org/10.1186/s12974-017-0905-7 |
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