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Treatment of severe hospital-acquired and ventilator-associated pneumonia: a systematic review of inclusion and judgment criteria used in randomized controlled trials

BACKGROUND: Hospital-acquired and ventilator-associated pneumonia (HAP/VAP) are often selected for randomized clinical trials (RCTs) aiming at new drug approval. Guidelines for the design of such RCTs have been repeatedly updated by regulatory agencies. We hypothesized that large variability in the...

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Detalles Bibliográficos
Autores principales: Weiss, Emmanuel, Essaied, Wafa, Adrie, Christophe, Zahar, Jean-Ralph, Timsit, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488424/
https://www.ncbi.nlm.nih.gov/pubmed/28655326
http://dx.doi.org/10.1186/s13054-017-1755-5