Genome-wide association study for birth, weaning and yearling weight in Colombian Brahman cattle

Genotypic and phenotypic data of 1,562 animals were analyzed to find genomic regions that potentially influence the birth weight (BW), weaning weight at seven months of age (WW) and yearling weight (YW) of Colombian Brahman cattle, with genotyping conducted using Illumina Bead chip array with 74,669...

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Detalles Bibliográficos
Autores principales: Martínez, Rodrigo, Bejarano, Diego, Gómez, Yolanda, Dasoneville, Romain, Jiménez, Ariel, Even, Gael, Sölkner, Johann, Mészáros, Gabor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2017
Materias:
Animal Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488450/
https://www.ncbi.nlm.nih.gov/pubmed/28534927
http://dx.doi.org/10.1590/1678-4685-GMB-2016-0017
Descripción
Sumario:Genotypic and phenotypic data of 1,562 animals were analyzed to find genomic regions that potentially influence the birth weight (BW), weaning weight at seven months of age (WW) and yearling weight (YW) of Colombian Brahman cattle, with genotyping conducted using Illumina Bead chip array with 74,669 SNPs. A Single Step Genomic BLUP (ssGBLP), approach was used to estimate the proportion of variance explained by each marker. Multiple regions scattered across the genome were found to influence weights at different ages, also dependent on the trait component (direct or maternal). The most interesting regions were connected to previously identified QTLs and genes, such as ADAMTSL3, CAPN2, CAPN2, FABP6, ZEB2 influencing growth and weight traits. The identified regions will contribute to the development and refinement of genomic selection programs for Zebu Brahman cattle in Colombia.

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