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Oligomeric tau-targeted immunotherapy in Tg4510 mice
BACKGROUND: Finding ways to reverse or prevent the consequences of pathogenic tau in the brain is of considerable importance for treatment of Alzheimer’s disease and other tauopathies. Immunotherapy against tau has shown promise in several mouse models. In particular, an antibody with selectivity fo...
Autores principales: | Schroeder, Sulana, Joly-Amado, Aurelie, Soliman, Ahlam, Sengupta, Urmi, Kayed, Rakiz, Gordon, Marcia N., Morgan, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488475/ https://www.ncbi.nlm.nih.gov/pubmed/28655349 http://dx.doi.org/10.1186/s13195-017-0274-6 |
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