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Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons

Herpes simplex virus 1 (HSV-1) uses latency in peripheral ganglia to persist in its human host, however, recurrent reactivation from this reservoir can cause debilitating and potentially life-threatening disease. Most studies of latency use live-animal infection models, but these are complex, multil...

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Detalles Bibliográficos
Autores principales: Pourchet, Aldo, Modrek, Aram S., Placantonakis, Dimitris G., Mohr, Ian, Wilson, Angus C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488658/
https://www.ncbi.nlm.nih.gov/pubmed/28594343
http://dx.doi.org/10.3390/pathogens6020024

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