Cargando…

Cavin-2 Functions as a Suppressive Regulator in TNF-induced Mesenchymal Stromal Cell Inflammation and Angiogenic Phenotypes

Tumour necrosis factor (TNF)-α activation of mesenchymal stromal cells (MSC) enhances their tumour-suppressive properties and tumour-homing ability. The molecular actors involved are unknown. We found that TNF induced MSC migration and tubulogenesis which correlated with a dose-dependent increase in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Annabi, Bayader, Zgheib, Alain, Annabi, Borhane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Stem Cell Research 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488782/ https://www.ncbi.nlm.nih.gov/pubmed/28024316 http://dx.doi.org/10.15283/ijsc16032

Ejemplares similares

A Role for the Cavin-3/Matrix Metalloproteinase-9 Signaling Axis in the Regulation of PMA-Activated Human HT1080 Fibrosarcoma Cell Neoplastic Phenotype
por: Toufaily, Chirine, et al.
Publicado: (2014)

The Primary Cilium as a Biomarker in the Hypoxic Adaptation of Bone Marrow-Derived Mesenchymal Stromal Cells: A Role for the Secreted Frizzled-Related Proteins
por: Proulx-Bonneau, Sébastien, et al.
Publicado: (2011)

A Concerted HIF-1α/MT1-MMP Signalling Axis Regulates the Expression of the 3BP2 Adaptor Protein in Hypoxic Mesenchymal Stromal Cells
por: Proulx-Bonneau, Sébastien, et al.
Publicado: (2011)

EGCG Prevents the Onset of an Inflammatory and Cancer-Associated Adipocyte-like Phenotype in Adipose-Derived Mesenchymal Stem/Stromal Cells in Response to the Triple-Negative Breast Cancer Secretome
por: Gonzalez Suarez, Narjara, et al.
Publicado: (2022)

A Transcriptional Regulatory Role for the Membrane Type-1 Matrix Metalloproteinase in Carcinogen-Induced Inflammasome Gene Expression
por: Sheehy, Samuel, et al.
Publicado: (2017)

A molecular signature for the G6PC3/SLC37A2/SLC37A4 interactors in glioblastoma disease progression and in the acquisition of a brain cancer stem cell phenotype
por: Torabidastgerdooei, Sima, et al.
Publicado: (2023)

MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells
por: Pratt, Jonathan, et al.
Publicado: (2022)

Resveratrol Targeting of Carcinogen-Induced Brain Endothelial Cell Inflammation Biomarkers MMP-9 and COX-2 is Sirt1-Independent
por: Annabi, Borhane, et al.
Publicado: (2012)

TH1902, a new docetaxel‐peptide conjugate for the treatment of sortilin‐positive triple‐negative breast cancer
por: Demeule, Michel, et al.
Publicado: (2021)

The TH1902 Docetaxel Peptide-Drug Conjugate Inhibits Xenografts Growth of Human SORT1-Positive Ovarian and Triple-Negative Breast Cancer Stem-like Cells
por: Demeule, Michel, et al.
Publicado: (2022)

Low intracellular ATP levels exacerbate carcinogen-induced inflammatory stress response and inhibit in vitro tubulogenesis in human brain endothelial cells
por: Tahanian, Elizabeth, et al.
Publicado: (2011)

Transcriptional targeting of sphingosine-1-phosphate receptor S1P2 by epigallocatechin-3-gallate prevents sphingosine-1-phosphate-mediated signaling in macrophage-differentiated HL-60 promyelomonocytic leukemia cells
por: Chokor, Rima, et al.
Publicado: (2014)

Periostin, a signal transduction intermediate in TGF-β-induced EMT in U-87MG human glioblastoma cells, and its inhibition by anthocyanidins
por: Ouanouki, Amira, et al.
Publicado: (2018)

EGCG Inhibits Adipose-Derived Mesenchymal Stem Cells Differentiation into Adipocytes and Prevents a STAT3-Mediated Paracrine Oncogenic Control of Triple-Negative Breast Cancer Cell Invasive Phenotype
por: Gonzalez Suarez, Narjara, et al.
Publicado: (2021)

Cavin1; a Regulator of Lung Function and Macrophage Phenotype
por: Govender, Praveen, et al.
Publicado: (2013)

Tetracycline Derivative Minocycline Inhibits Autophagy and Inflammation in Concanavalin-A-Activated Human Hepatoma Cells
por: Desjarlais, Michel, et al.
Publicado: (2014)

A Signaling Crosstalk Links SNAIL to the 37/67 kDa Laminin-1 Receptor Ribosomal Protein SA and Regulates the Acquisition of a Cancer Stem Cell Molecular Signature in U87 Glioblastoma Neurospheres
por: Gresseau, Loraine, et al.
Publicado: (2022)

New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells
por: Charfi, Cyndia, et al.
Publicado: (2021)

The Peptide-Drug Conjugate TH1902: A New Sortilin Receptor-Mediated Cancer Therapeutic against Ovarian and Endometrial Cancers
por: Currie, Jean-Christophe, et al.
Publicado: (2022)

Computational Methods for Structure-to-Function Analysis of Diet-Derived Catechins-Mediated Targeting of In Vitro Vasculogenic Mimicry
por: Uthamacumaran, Abicumaran, et al.
Publicado: (2021)

EGCG Prevents the Transcriptional Reprogramming of an Inflammatory and Immune-Suppressive Molecular Signature in Macrophage-like Differentiated Human HL60 Promyelocytic Leukemia Cells
por: Kassouri, Celia, et al.
Publicado: (2022)

Pharmacological targeting of β-adrenergic receptor functions abrogates NF-κB signaling and MMP-9 secretion in medulloblastoma cells
por: Annabi, Borhane, et al.
Publicado: (2010)

Epigallocatechin-3-Gallate Prevents the Acquisition of a Cancer Stem Cell Phenotype in Ovarian Cancer Tumorspheres through the Inhibition of Src/JAK/STAT3 Signaling
por: Rodriguez Torres, Sahily, et al.
Publicado: (2023)

EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells
por: Gonzalez Suarez, Narjara, et al.
Publicado: (2023)

Targeting Ovarian Cancer Cell Cytotoxic Drug Resistance Phenotype with Xanthium strumarium L. Extract
por: Francisco Fernandez, Marbelis, et al.
Publicado: (2019)

The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression
por: Belkaid, Anissa, et al.
Publicado: (2006)

The lectin concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKγ/NF-κB-dependent pathway
por: Sina, Asmaa, et al.
Publicado: (2010)

A MT1-MMP/NF-κB signaling axis as a checkpoint controller of COX-2 expression in CD133(+) U87 glioblastoma cells
por: Annabi, Borhane, et al.
Publicado: (2009)

Impact of Concanavalin-A-Mediated Cytoskeleton Disruption on Low-Density Lipoprotein Receptor-Related Protein-1 Internalization and Cell Surface Expression in Glioblastomas
por: Nanni, Samuel Burke, et al.
Publicado: (2016)

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
por: McMahon, Kerrie-Ann, et al.
Publicado: (2019)

Flavonoids targeting of IκB phosphorylation abrogates carcinogen-induced MMP-9 and COX-2 expression in human brain endothelial cells
por: Tahanian, Elizabeth, et al.
Publicado: (2011)

Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
por: Williams, Jamie J. L., et al.
Publicado: (2018)

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes
por: Bastiani, Michele, et al.
Publicado: (2009)

MT1-MMP Cooperates with TGF-β Receptor-Mediated Signaling to Trigger SNAIL and Induce Epithelial-to-Mesenchymal-like Transition in U87 Glioblastoma Cells
por: Djediai, Souad, et al.
Publicado: (2021)

Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice
por: Abusarah, Jamilah, et al.
Publicado: (2021)

A phosphoinositide-binding cluster in cavin1 acts as a molecular sensor for cavin1 degradation
por: Tillu, Vikas A., et al.
Publicado: (2015)

Cavin3 Suppresses Breast Cancer Metastasis via Inhibiting AKT Pathway
por: An, Xin, et al.
Publicado: (2020)

UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1
por: Cen, Xiaotong, et al.
Publicado: (2022)

Caveolae, Caveolins, Cavins, and Endothelial Cell Function: New Insights
por: Sowa, Grzegorz
Publicado: (2012)

Cavin-3 Knockout Mice Show that Cavin-3 Is Not Essential for Caveolae Formation, for Maintenance of Body Composition, or for Glucose Tolerance
por: Liu, Libin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_f0hv9hggirpdbnt5i581edskui