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Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy

PURPOSE: To investigate the molecular basis of posterior polymorphous corneal dystrophy (PPCD) by examining the PPCD transcriptome and the effect of decreased ZEB1 expression on corneal endothelial cell (CEnC) gene expression. METHODS: Next-generation RNA sequencing (RNA-seq) analyses of corneal end...

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Detalles Bibliográficos
Autores principales: Chung, Doug D., Frausto, Ricardo F., Lin, Benjamin R., Hanser, Evelyn M., Cohen, Zack, Aldave, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488878/
https://www.ncbi.nlm.nih.gov/pubmed/28654985
http://dx.doi.org/10.1167/iovs.17-21423