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Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology
Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States and mechanisms of liver injury induced by APAP overdose have been the focus of extensive investigation. Studies in the mouse model, which closely reproduces the human condition, have shown that hepatot...
Autores principales: | Ramachandran, Anup, Jaeschke, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Whioce Publishing Pte. Ltd.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489132/ https://www.ncbi.nlm.nih.gov/pubmed/28670625 |
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