Mycobacteria induce TPL-2 mediated IL-10 in IL-4-generated alternatively activated macrophages

IL-4 drives expansion of Th2 cells that cause generation of alternatively activated macrophages (AAMs). Filarial infections are established early in life, induce increased IL-4 production are co-endemic with tuberculosis (TB). We sought to understand, therefore, how mycobacteria are handled in the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Chatterjee, Soumya, Talaat, Kawsar R., van Seventer, Emily E., Feng, Carl G., Scott, Alan L., Jedlicka, Anne, Dziedzic, Amanda, Nutman, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489173/
https://www.ncbi.nlm.nih.gov/pubmed/28658262
http://dx.doi.org/10.1371/journal.pone.0179701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489173/
https://www.ncbi.nlm.nih.gov/pubmed/28658262
http://dx.doi.org/10.1371/journal.pone.0179701

Ejemplares similares