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Mycobacteria induce TPL-2 mediated IL-10 in IL-4-generated alternatively activated macrophages

IL-4 drives expansion of Th2 cells that cause generation of alternatively activated macrophages (AAMs). Filarial infections are established early in life, induce increased IL-4 production are co-endemic with tuberculosis (TB). We sought to understand, therefore, how mycobacteria are handled in the c...

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Detalles Bibliográficos
Autores principales:	Chatterjee, Soumya, Talaat, Kawsar R., van Seventer, Emily E., Feng, Carl G., Scott, Alan L., Jedlicka, Anne, Dziedzic, Amanda, Nutman, Thomas B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489173/ https://www.ncbi.nlm.nih.gov/pubmed/28658262 http://dx.doi.org/10.1371/journal.pone.0179701

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