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Structure and function of Helicobacter pylori CagA, the first-identified bacterial protein involved in human cancer

Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor of gastric cancer. The cagA gene-encoded CagA protein is delivered into gastric epithelial cells via bacterial type IV secretion, where it undergoes tyrosine phosphorylation at the Glu-Pro-Ile-Tyr-Ala (EPIY...

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Detalles Bibliográficos
Autor principal:	HATAKEYAMA, Masanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japan Academy 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489429/ https://www.ncbi.nlm.nih.gov/pubmed/28413197 http://dx.doi.org/10.2183/pjab.93.013

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