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Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells
Even when the body is stationary, the whole retinal image is always in motion by fixational eye movements and saccades that move the eye between fixation points. Accumulating evidence indicates that the brain is equipped with specific mechanisms for compensating for the global motion induced by thes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Academy
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489431/ https://www.ncbi.nlm.nih.gov/pubmed/28413199 http://dx.doi.org/10.2183/pjab.93.015 |
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author | MATSUMOTO, Akihiro TACHIBANA, Masao |
author_facet | MATSUMOTO, Akihiro TACHIBANA, Masao |
author_sort | MATSUMOTO, Akihiro |
collection | PubMed |
description | Even when the body is stationary, the whole retinal image is always in motion by fixational eye movements and saccades that move the eye between fixation points. Accumulating evidence indicates that the brain is equipped with specific mechanisms for compensating for the global motion induced by these eye movements. However, it is not yet fully understood how the retina processes global motion images during eye movements. Here we show that global motion images evoke novel coordinated firing in retinal ganglion cells (GCs). We simultaneously recorded the firing of GCs in the goldfish isolated retina using a multi-electrode array, and classified each GC based on the temporal profile of its receptive field (RF). A moving target that accompanied the global motion (simulating a saccade following a period of fixational eye movements) modulated the RF properties and evoked synchronized and correlated firing among local clusters of the specific GCs. Our findings provide a novel concept for retinal information processing during eye movements. |
format | Online Article Text |
id | pubmed-5489431 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Japan Academy |
record_format | MEDLINE/PubMed |
spelling | pubmed-54894312017-08-09 Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells MATSUMOTO, Akihiro TACHIBANA, Masao Proc Jpn Acad Ser B Phys Biol Sci Original Article Even when the body is stationary, the whole retinal image is always in motion by fixational eye movements and saccades that move the eye between fixation points. Accumulating evidence indicates that the brain is equipped with specific mechanisms for compensating for the global motion induced by these eye movements. However, it is not yet fully understood how the retina processes global motion images during eye movements. Here we show that global motion images evoke novel coordinated firing in retinal ganglion cells (GCs). We simultaneously recorded the firing of GCs in the goldfish isolated retina using a multi-electrode array, and classified each GC based on the temporal profile of its receptive field (RF). A moving target that accompanied the global motion (simulating a saccade following a period of fixational eye movements) modulated the RF properties and evoked synchronized and correlated firing among local clusters of the specific GCs. Our findings provide a novel concept for retinal information processing during eye movements. The Japan Academy 2017-04-11 /pmc/articles/PMC5489431/ /pubmed/28413199 http://dx.doi.org/10.2183/pjab.93.015 Text en © 2017 The Japan Academy This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article MATSUMOTO, Akihiro TACHIBANA, Masao Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells |
title | Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells |
title_full | Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells |
title_fullStr | Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells |
title_full_unstemmed | Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells |
title_short | Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells |
title_sort | rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489431/ https://www.ncbi.nlm.nih.gov/pubmed/28413199 http://dx.doi.org/10.2183/pjab.93.015 |
work_keys_str_mv | AT matsumotoakihiro rapidandcoordinatedprocessingofglobalmotionimagesbylocalclustersofretinalganglioncells AT tachibanamasao rapidandcoordinatedprocessingofglobalmotionimagesbylocalclustersofretinalganglioncells |