A Quantitative Study of Internal and External Interactions of Homodimeric Glucocorticoid Receptor Using Fluorescence Cross-Correlation Spectroscopy in a Live Cell

Glucocorticoid receptor (GRα) is a well-known ligand-dependent transcription-regulatory protein. The classic view is that unliganded GRα resides in the cytoplasm, relocates to the nucleus after ligand binding, and then associates with a specific DNA sequence, namely a glucocorticoid response element...

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Detalles Bibliográficos
Autores principales: Tiwari, Manisha, Oasa, Sho, Yamamoto, Johtaro, Mikuni, Shintaro, Kinjo, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489515/
https://www.ncbi.nlm.nih.gov/pubmed/28659593
http://dx.doi.org/10.1038/s41598-017-04499-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489515/
https://www.ncbi.nlm.nih.gov/pubmed/28659593
http://dx.doi.org/10.1038/s41598-017-04499-7

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