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Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance

Knowledge of normal and abnormal flow patterns in the human cardiovascular system increases our understanding of normal physiology and may help unravel the complex pathophysiological mechanisms leading to cardiovascular disease. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) has...

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Autores principales: Kamphuis, Vivian P., Westenberg, Jos J. M., van der Palen, Roel L. F., Blom, Nico A., de Roos, Albert, van der Geest, Rob, Elbaz, Mohammed S. M., Roest, Arno A. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489572/
https://www.ncbi.nlm.nih.gov/pubmed/27888419
http://dx.doi.org/10.1007/s10554-016-1031-9
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author Kamphuis, Vivian P.
Westenberg, Jos J. M.
van der Palen, Roel L. F.
Blom, Nico A.
de Roos, Albert
van der Geest, Rob
Elbaz, Mohammed S. M.
Roest, Arno A. W.
author_facet Kamphuis, Vivian P.
Westenberg, Jos J. M.
van der Palen, Roel L. F.
Blom, Nico A.
de Roos, Albert
van der Geest, Rob
Elbaz, Mohammed S. M.
Roest, Arno A. W.
author_sort Kamphuis, Vivian P.
collection PubMed
description Knowledge of normal and abnormal flow patterns in the human cardiovascular system increases our understanding of normal physiology and may help unravel the complex pathophysiological mechanisms leading to cardiovascular disease. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) has emerged as a suitable technique that enables visualization of in vivo blood flow patterns and quantification of parameters that could potentially be of prognostic value in the disease process. In this review, current image processing tools that are used for comprehensive visualization and quantification of blood flow and energy distribution in the heart and great vessels will be discussed. Also, imaging biomarkers extracted from 4D flow CMR will be reviewed that have been shown to distinguish between normal and abnormal flow patterns. Furthermore, current applications of 4D flow CMR in the heart and great vessels will be discussed, showing its potential as an additional diagnostic modality which could aid in disease management and timing of surgical intervention.
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spelling pubmed-54895722017-07-03 Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance Kamphuis, Vivian P. Westenberg, Jos J. M. van der Palen, Roel L. F. Blom, Nico A. de Roos, Albert van der Geest, Rob Elbaz, Mohammed S. M. Roest, Arno A. W. Int J Cardiovasc Imaging Original Paper Knowledge of normal and abnormal flow patterns in the human cardiovascular system increases our understanding of normal physiology and may help unravel the complex pathophysiological mechanisms leading to cardiovascular disease. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) has emerged as a suitable technique that enables visualization of in vivo blood flow patterns and quantification of parameters that could potentially be of prognostic value in the disease process. In this review, current image processing tools that are used for comprehensive visualization and quantification of blood flow and energy distribution in the heart and great vessels will be discussed. Also, imaging biomarkers extracted from 4D flow CMR will be reviewed that have been shown to distinguish between normal and abnormal flow patterns. Furthermore, current applications of 4D flow CMR in the heart and great vessels will be discussed, showing its potential as an additional diagnostic modality which could aid in disease management and timing of surgical intervention. Springer Netherlands 2016-11-25 2017 /pmc/articles/PMC5489572/ /pubmed/27888419 http://dx.doi.org/10.1007/s10554-016-1031-9 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Kamphuis, Vivian P.
Westenberg, Jos J. M.
van der Palen, Roel L. F.
Blom, Nico A.
de Roos, Albert
van der Geest, Rob
Elbaz, Mohammed S. M.
Roest, Arno A. W.
Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance
title Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance
title_full Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance
title_fullStr Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance
title_full_unstemmed Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance
title_short Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance
title_sort unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489572/
https://www.ncbi.nlm.nih.gov/pubmed/27888419
http://dx.doi.org/10.1007/s10554-016-1031-9
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