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Postnatal Maturation of the Glomerular Filtration Rate in Conventional Growing Piglets As Potential Juvenile Animal Model for Preclinical Pharmaceutical Research

Adequate animal models are required to study the preclinical pharmacokinetics (PK), pharmacodynamics (PD) and safety of drugs in the pediatric subpopulation. Over the years, pigs were presented as a potential animal model, since they display a high degree of anatomical and physiological similarities...

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Detalles Bibliográficos
Autores principales:	Gasthuys, Elke, Devreese, Mathias, Millecam, Joske, Sys, Stanislas, Vanderperren, Katrien, Delanghe, Joris, Vande Walle, Johan, Heyndrickx, Marjolein, Croubels, Siska
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489626/ https://www.ncbi.nlm.nih.gov/pubmed/28706488 http://dx.doi.org/10.3389/fphar.2017.00431

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