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NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors
Yes-associated protein (YAP) is a downstream target of the Hippo pathway and has been found to be oncogenic driving many cancers into developing metastatic phenotypes leading to poor survival outcomes. This study investigated if YAP expression is associated with drug resistance in two non-small cell...
Autores principales: | McGowan, Marc, Kleinberg, Lilach, Halvorsen, Ann Rita, Helland, Åslaug, Brustugun, Odd Terje |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489647/ https://www.ncbi.nlm.nih.gov/pubmed/28680534 http://dx.doi.org/10.18632/genesandcancer.136 |
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