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NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors

Yes-associated protein (YAP) is a downstream target of the Hippo pathway and has been found to be oncogenic driving many cancers into developing metastatic phenotypes leading to poor survival outcomes. This study investigated if YAP expression is associated with drug resistance in two non-small cell...

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Detalles Bibliográficos
Autores principales: McGowan, Marc, Kleinberg, Lilach, Halvorsen, Ann Rita, Helland, Åslaug, Brustugun, Odd Terje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489647/
https://www.ncbi.nlm.nih.gov/pubmed/28680534
http://dx.doi.org/10.18632/genesandcancer.136

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